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Tartrazine and sperm count

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    Mountain Dew does not kill sperm, contrary to popular myth. There are two reasons why some people mistakenly believe Mountain Dew kills sperm — caffeine and yellow dye 5. These ingredients are in Mountain Dew but not in high enough quantities to kill sperm. Though Mountain Dew does not affect fertility, many other unrelated factors can lower sperm counts and affect male fertility.
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    Tartrazine - Wikipedia

    Food Yellow 4 FY4 is a lemon-yellow-colored synthetic organic azo dye, which is used widely for imparting pleasant and attractive appearance to foods and cosmetics. The present study aimed at evaluating the possible mechanism underlying the FY4-induced reprotoxicity in rats, and the potential supportive role of royal jelly RJ or cod liver oil CLO , which is a natural remedy with several pharmacological benefits, against induced toxicity. Forty-eight male rats were divided into different groups-the control group, the CLO group 0. Semen analysis, serum hormones, and enzyme activities were estimated. Furthermore, co-localization of DMC1 and ssDNA, which reflected apoptotic induction in the leptotene and zygotene spermatocytes, respectively, was observed to have markedly elevated in the FY4 treated rats, with fewer PCNA-positive and SOX9-positive cells and higher ssDNA-positive cells in the seminiferous epithelium in comparison to the control groups. Interestingly, co-treatment with CLO or RJ exhibited healthy sperms and restored their features, activated the enzyme production, and raised the levels of sexual hormones. In addition, both RJ and CLO restored the features of the testicular tissue as observed under a light microscope, and limited the apoptosis as observed through antibody staining.
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    The year was and teenage boys were under a spell cast by Mountain Dew. Rumors flew that one of the very popular soda's synthetic food dyes decreased sperm count ; as a result, some sexually-active teens began binge-drinking the alleged spermicide as their only form of birth control. That year, the rumor gained so much traction that the Wall Street Journal published an article chronicling susceptible teens' belief in it. According to the urban legend, the soda lowers sperm count and thus works as pre-coital contraception because of the soda's dye, Yellow No. Pepsi Cola produces both Gatorade and Mountain Dew; they did not return Broadly's request for comment.
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    Unfounded rumors about artificial food additives being unsafe are typically harmless, because consumers can't hurt themselves by cutting back on a chemical that is devoid of nutritional value. But in the case of the synthetic food dye tartrazine, better known in the United States as Yellow No. Meanwhile, consumers overlooked another, more insidious, potential side effect of the chemical.
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